The Nissan Cube has a rounded exterior and curved styling. This is most striking in the rear bumper area, in the asymmetrical rear window, which wraps around to the passenger side, and in the oval-shaped driver and front passenger windows. The rear hatch is hinged to open along its vertical axis, towards the curb. This helps loading and unloading when street parking in a crowded urban environment.

Seating capacity is at five. According to Nissan designers, the interior is inspired by the enveloping curves of a Jacuzzi in order to promote a comfortable and social atmosphere. Design cues include a water ripple motif that appears in the headliner and is repeated in details like the speaker covers and cup holders. Nissan has developed an extended line of accessories for Cube to encourage personalization. These include multicolor appliqués that can be placed around air vents and window switches, utility hooks and elastic bands in different colors, ariable color LED accent lighting for cup holders, and a piece of color-coordinated shag carpet that sits in a shallow well on the top of the dash.

Nissan Cube is built on Nissan's front-wheel-drive & platform and powered by a 122-horsepower, 1.8-liter four-cylinder engine. Its available with a 6-speed manual transmission or Nissan's automatic CVT (Continuously Variable Transmission). The Cube is capable of US 28mpg city, and US 30mpg highway with its Xtronic CVT transmission. The e-4WD trim contains an electric rear wheel drive motor to assist the gasoline engine powered front wheels.

There are four Cube trim levels, the Cube 1.8, 1.8S, 1.8SL and culminating 1.8 Krom. Every Nissan is backed by a 36-month/36,000-mile limited vehicle coverage and a 5-year/60,000-mile limited power train coverage.